Phytochemicals and Antioxidant Activities

Optimized Kakadu Plum Extracts Inhibit Intracellular Oxidative Stress in Canine Small Intestinal Cell Model

This study optimizes Kakadu plum extract preparation and shows it reduces oxidative stress in canine intestinal cells.

Species and Accession Diversity of Secondary Metabolites and Antioxidant Activity in Legume Sprouts

The paper evaluates antioxidant activity and secondary metabolites in legume sprouts across species and accessions, finding significant variation in properties and metabolite profiles.

A Validated LC-MS/MS Method for Quantifying Phenolic Acids, Lignans, and Enterolignans from Human Fecal Samples

This paper develops and validates an LC-MS/MS method to quantify phenolic acids, lignans, and enterolignans in human fecal samples, finding that catechol-containing phenolic acids are more abundant than guaiacols.

Enhancing the biological activity of polyphenols based on understanding their chemistry

This study investigates how hydroxyl groups and lipophilic environments affect the toxicity of polyphenols in yeast, finding that more hydroxyl groups and lipid solvents increase toxicity.

Antioxidant capacity of Catechinopyranocyanidins derived from adzuki beans

This study evaluates the antioxidant capacity of catechinopyranocyanidins from adzuki beans using in vitro assays and cell culture experiments, revealing their cytoprotective effects against oxidative stress.

Phytochemical profiling, antioxidant capacity, and in vivo safety assessment of Warrigal spinach (Tetragonia tetragonioides) and Kensington Pride mango (Mangifera indica) extracts using Zebrafish larvae

This study evaluates the antioxidant capacity and safety of Warrigal spinach and Kensington Pride mango extracts using zebrafish larvae, finding higher antioxidant activity in spinach but no direct link between antioxidant capacity and toxicity.

Assessment of inter-individual variation in metabolism of flavonoids from bilberry and grape seed extracts using an in vitro digestion and faecal fermentation model

This study assesses inter-individual variation in flavonoid metabolism using in vitro digestion and faecal fermentation models with bilberry, grape seed, and combined extracts.

A mixture of plant polyphenols unexpectedly aggravates liver metastasis of colorectal cancer in mice

This study shows that a plant polyphenol mixture accelerates liver metastasis in mice, suggesting potential immunomodulatory effects that require validation in immunocompetent models.

Spinach (Spinacia oleracea L.) Flavonoids Are Hydrolyzed During Digestion and Their Bioaccessibility Is Under Stronger Genetic Control than Raw Material Content

This study quantifies flavonoid diversity and bioaccessibility in spinach, finding that bioaccessibility has stronger genetic control than raw material content.

Development and validation of ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method to quantify monotropein in blueberries

The paper develops and validates an UPLC-MS/MS method to quantify monotropein in blueberries, showing high recovery and repeatability across 28 cultivars.

Quantification of bioactive compounds in the juices of 21 American elderberry cultivars

This study develops a UHPLC-MS/MS method to quantify bioactive compounds in 21 American elderberry cultivars, identifying cultivar 1199 as high in cyanidin-based anthocyanins.

Optimization of Microwave-Assisted Extraction of AntioxidantCompounds from Vitex negundo Leaves using Response SurfaceMethodology

This study optimizes microwave-assisted extraction of antioxidants from Vitex negundo leaves using response surface methodology, finding optimal conditions that maximize total phenolic and flavonoid content and antioxidant capacity.

A Comprehensive UHPLC-MS/MS and Extraction Method for Spinach (Spinacia oleracea) Flavonoids

The paper develops and validates a high-throughput UHPLC-MS/MS method to quantify 39 spinach flavonoids, showing comparable results to traditional methods and providing first quantitative reports for many compounds.

Individual variability in polyphenol metabolite production: A dietary challenge study

This study examines variability in polyphenol metabolite production after a controlled dietary challenge and finds significant individual differences and low agreement between tertiles of metabolite output.

Evaluation of the antioxidant activity of biologically-active compositions based on plant metabolites produced by in vitro cell cultures

This study evaluates the antioxidant activity of polyphenol compositions from in vitro cell cultures using ABTS and DPPH methods, finding that quercetin has the highest activity and mixtures with higher quercetin content show better results.

Pro-oxidant influence of quercetin supplementation in Saccharomyces cerevisiae

This study investigates quercetin's pro-oxidant effects in yeast, showing mitochondrial dysfunction and increased oxidative stress.

In vitro antioxidant and anti-inflammatory activities, total phenolic and flavonoid contents of Anadenanthera colubrina from Northern Peru

This study evaluates the antioxidant and anti-inflammatory properties of Anadenanthera colubrina bark extract, finding high antioxidant activity and significant inhibition of oxidative stress markers.

Inhibition of Myoglobin Oxidation by Food Grade Botanical Antioxidant Formulations

This study evaluates the antioxidant effects of green tea and acerola extracts on myoglobin oxidation at different temperatures, finding that acerola is more effective at lower temperatures while green tea becomes more active at higher temperatures.

Comparative antioxidant activity of Ocimum gratissimum and Jatropha tanjorensis 2024.

This study compares the antioxidant activity of Ocimum gratissimum and Jatropha tanjorensis extracts, finding synergistic effects when combined.

Exploring American Elderberry Compounds for Antioxidant, Antiviral, and Antibacterial Properties Through High-Throughput Screening Assays Combined with Untargeted Metabolomics

This study identifies bioactive compounds in American elderberry juice using metabolomics and high-throughput assays, revealing antioxidant, antiviral, and antibacterial properties.