Developmental BiologyDevelopmentPeer-reviewed
✦ In-depth digest
Human vein-to-artery endothelial cell fate transition is driven by VEGF/ERK activation and PI3K inhibition
Zhainib A Amir-Ugokwe, A. L. Pyke, Emily Trimm…·Kristy Red‐Horse
A stem cell-derived human vein-to-artery endothelial conversion model mirrors angiogenesis-derived embryonic arteries; VEGF plus PI3K inhibition alone yields 92% DLL4+CXCR4+ endothelium by 48 hours.
1 citation