A peptidomimetic inhibitor blocks Vibrio cholerae adhesin FrhA.
Mingyu Wang, Charity Deborah Yongo-Luwawa, Laura Zhang, Ryu F Williston, John Presley, Zhaleh Mehboodi, Dieter Peter Reinhardt, Karl E. Klose, William D. Lubell, Shuaiqi Guo
This study designs a peptidomimetic inhibitor that blocks Vibrio cholerae adhesin FrhA, showing nanomolar binding affinity and reduced biofilm formation.
bioRxiv · Oct 27, 2026 · PreprintBiochemistry