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This paper develops a feature-mask-based CNN to detect freezing of gait subtypes, finding that manifestation-specific models improve detection sensitivity and specificity compared to general models.

This study compares the lethality-inducing potential of Bax, Casp3, and Casp9 in mouse early embryos and finds Bax most effective in causing embryo death.

The paper computationally designs monomeric Fc variants with distinct pH-responsive FcRn-binding profiles, showing enhanced binding at acidic pH and weak binding at neutral pH.

This paper identifies hemodynamic and geometric predictors of favorable response to flow diverter stent treatment in cerebral aneurysms using computational fluid dynamics simulations.

This paper introduces a breast duct-on-chip model to simulate invasive ductal carcinoma and test chemotherapies, finding that Paclitaxel inhibits invasion in 30% of tests and reveals flow-like cancer cell migration.

This paper develops a collagen-based gut-on-chip to model intestinal barrier function and host-pathogen interactions, showing successful cell differentiation and infection replication.

This study shows that MVL5-based micellar nanoparticles enhance paclitaxel solubility and cytotoxicity in cancer cells, with PEGylation improving cellular uptake and penetration.

This study examines intervertebral disc (IVD) impairments in a mouse model of Alzheimer's Disease, finding no increased degeneration but altered mechanical properties and volume.

This study uses hiPSC-derived atrial cardiomyocytes and fibroblasts to model atrial fibrillation through intermittent tachypacing, showing increased AP frequency and fibrosis markers.

This paper investigates how elevated CO2 enhances organic-carbon consumption and confectionery-waste valorization in Galdieria algae under mixotrophy.

This study investigates bone metabolism, muscle composition, and muscle-bone crosstalk in rat models of brachial plexus birth injury, finding distinct effects between postganglionic and preganglionic injuries.

This paper introduces a confined culture system to generate innervated human gut organoids that mature faster and support transplantation, enhancing engraftment and function.

timePlex increases LC-MS throughput by multiplexing samples in the time domain, achieving combinatorial scaling and enabling high-throughput proteomics.

This study examines how brachial plexus birth injury affects trabecular bone microstructure and morphology in different locations, showing location-dependent detriments and differential effects based on injury type and limb disuse.

This study shows high glucose and fluid shear stress together enhance metastatic breast cancer cell migration, mediated by focal adhesion kinase.

PSMtags enhance peptide detection and sequence identification in proteomics, enabling 9-plexDIA and significantly increasing sample throughput.

This paper introduces CereBRLSIM, a digital twin that predicts cerebral blood flow and CVR mechanisms in neurocritical care patients with higher accuracy than machine learning models.

This paper develops a calibration-free P300 BCI system with real-time performance comparable to offline benchmarks, using pre-trained models and a small electrode setup.

The paper validates ephaptic coupling in human neuronal circuits using a reproducible in vitro method, showing reduced action potential velocity and increased synchronization.

This paper shows that alternating 2D and 3D culture reduces cell size and extends the lifespan of placenta-derived MSCs while preserving their immunomodulatory function.