Author

Sherwin Roshan

University of California, Santa Barbara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Cyrus R. SafinyaiD· 2 shared Jessica Douglas· 2 shared Kai K. EwertiD· 2 shared Ramon Perez· 2 shared William S. FisheriD· 2 shared Anna Goldstein· 1 shared Aria GhasemizadehiD· 1 shared Logan RobertsiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioengineering

Cyrus R. SafinyaORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintMay 24, 2025

Multivalent Lipid MVL5 Micellar Nanoparticles Exhibit Dramatically Increased Loading of Paclitaxel with PEGylation Enhancing Human Cancer Cell Penetration Depth and Cytotoxicity

William S. Fisher, Aria Ghasemizadeh, Sherwin Roshan…·Cyrus R. Safinya

This study shows that MVL5-based micellar nanoparticles enhance paclitaxel solubility and cytotoxicity in cancer cells, with PEGylation improving cellular uptake and penetration.

DOI 10.1101/2025.05.24.655953

humanexperimental assay

𝕏 PostBluesky

BiophysicsLangmuirPeer-reviewedFeb 13, 2025

Acidic Conditions Promote Clustering of Cancer Cell Derived Extracellular Vesicles and Enhance their Fusion with Synthetic Liposomes

William S. Fisher, Jessica Douglas, Sherwin Roshan…·Cyrus R. Safinya

This paper demonstrates that acidic conditions enhance EV-liposome fusion without additional fusogens, supported by FRET and microscopy, and suggests implications for drug delivery.

10 citations

humanbulk RNA-seq

𝕏 PostBluesky