Jennifer K. Briggs

This study shows that restoring gap junction coupling does not fully recover functional beta-cell sub-populations under diabetogenic conditions.

CRISP improves cell segmentation accuracy in dense calcium imaging data by refining user-drawn masks and automatically identifying cell outlines.

This paper introduces CereBRLSIM, a digital twin that predicts cerebral blood flow and CVR mechanisms in neurocritical care patients with higher accuracy than machine learning models.

This paper uses CMOS microelectrode arrays to study electrical signal propagation in mouse islets, finding glucose-dependent changes in wave velocity and identifying a subpopulation of active cells.

This paper uses 3D light-sheet imaging to study β-cell subpopulations and their role in islet Ca2+ oscillations, finding that glucokinase activity patterns leader cells at the periphery.