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LASSO is a sequence-selective biomolecule isolation platform that achieves high efficiency, low off-target effects, and cost-effectiveness for diverse targets.

This study uses snRNAseq to identify cell-specific pro-repair responses induced by an infusible ECM biomaterial after myocardial infarction.

This study examines how physiological response functions (PRFs) vary across individuals and brain regions in fMRI data and shows that allowing spatial and subject-specific variability improves PRF model performance.

This study shows that endothelial cell stiffness and type influence biomechanically-induced transcellular pore formation in Schlemms canal cells.

This paper develops a composite hydrogel (C-gel) that enables localized in situ gelation and sustained nanocarrier release in the anterior chamber of the eye, showing 90% polymer retention and over a month of sustained release in mice.

This study uses an ex vivo hindlimb culturing platform with dynamic mechanical loading and PNCOL injection to enhance muscle regeneration and reduce inflammation in critical-size TA muscle defects.

The paper introduces two orthogonal RNA-regulated destabilization domains for three-color mRNA imaging in mammalian cells with minimal RNA perturbation.

This study investigates how ultrasound and enzymes affect amyloid microclots, finding that ultrasound alone is more effective than enzymes in disrupting clot structures.

This paper develops a miniaturized flow chamber to assess calcification in biohybrid implants under physiological flow conditions, showing similar calcification in bovine pericardium and no calcification in polycarbonate urethane.

This paper develops a bioprinted hydrogel graft with a mineral gradient to mimic the osteochondral interface, showing structural and mechanical properties similar to native tissue.

This paper develops a 3D patient-derived co-culture model of early peritoneal endometriosis to study lesion formation and progression.

This paper develops a hydrogel microneedle array-based transdermal dressing system that continuously monitors chronic wound conditions and delivers therapy.

This study shows that biomimetic fractal topography improves podocyte maturation in vitro by enhancing marker expression, cell polarity, and ECM remodeling via YAP signaling.

This paper develops a sulfonated interpenetrating polymer network to restore degraded cartilage ECM properties and protect against further degradation in osteoarthritis.

This paper develops a high-throughput optogenetic assay for skeletal muscle exercise studies, revealing transcriptional responses to optical stimulation and hypoxia.

This study validates acoustic analysis of stem impaction sounds to assess primary stability in uncemented hip prostheses, showing correlation with biomechanical micromotions.

The paper develops an NFC-enabled sensor for rapid, cost-effective detection of free asparagine in food to reduce acrylamide formation.

This paper introduces an autonomous software framework for optimizing monoclonal antibody production by integrating Bayesian design, digital twins, and parallel bioreactors to improve process efficiency.

This study develops a mechanoregulatory model to predict how mechanical loading affects glycosaminoglycan content in human cartilage, showing increased GAG production in damaged cartilage under physiological loading.