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Individual differences reveal shared computational structure in perceptual decision-making

The paper uses population-level individual differences to discover shared computational components in perceptual decision-making, revealing a six-dimensional structure across datasets.

Multimodal cellular context enables molecular phenotyping from single-molecule trajectories

The paper introduces MIST, a framework that integrates single-molecule trajectory data with cellular context to improve molecular phenotyping in E. coli.

Real-time detection of N2 and N3 sleep from scalp and intracranial EEG

This paper develops a real-time sleep stage classifier for N2 and N3 sleep using scalp and intracranial EEG, showing high accuracy and informing stimulation timing.

Beyond Terrestrial Carnivores: Olfactory Bulb Anatomy in a Semi-Aquatic Mammal

This study characterizes the olfactory bulb anatomy of the Asian small-clawed otter, revealing a highly developed main olfactory bulb and a small, neurochemically distinct accessory olfactory bulb.

Hyperactivity preferentially disrupts scotopic retinal circuits in the early stages of diabetic retinopathy

This study identifies scotopic retinal circuit dysfunction in early diabetic retinopathy, linking hyperactivity to rod bipolar cell abnormalities and visual impairment under low-light conditions.

Auditory Evoked Potentials Differ from Controls and Correlate with Aspects of Cognition in Kabuki Syndrome and Rubinstein-Taybi Syndrome

This study examines auditory evoked potentials in Kabuki syndrome and Rubinstein-Taybi syndrome, finding differences from controls and correlations with cognitive aspects.

QRAFT: Scaling coalescent-based species tree inference to one million taxa

QRAFT efficiently infers species trees for up to a million taxa using coalescent-based methods, outperforming existing tools in speed and memory usage.

Neonatal NMDA receptor blockade disrupts prefrontal cortical regulation of social affective behavior: implications for schizophrenia

This study shows that neonatal NMDA receptor blockade impairs social affective behavior in rats, linked to reduced parvalbumin interneurons in the medial prefrontal cortex.

Probing EEG Foundation Model Attention Maps for Lightweight Interpretable Emotion Recognition

This paper proposes a lightweight, interpretable method for emotion recognition using EEG foundation models by analyzing attention maps, achieving competitive performance with fewer computations.

Targeting REV1 Exposes Context-Dependent Therapeutic Responses in Colorectal Cancer

This study shows that targeting REV1 in colorectal cancer enhances chemotherapy sensitivity in a context-dependent manner and inhibits organoid growth.

Hierarchical Temporal Transformer for Cancer Grade Prediction and Cross-Cancer Transfer Learning from Pathology Reports

This paper introduces a hierarchical temporal transformer for cancer grade prediction from pathology reports, showing improved performance across cancer types and using visit timing when identifiable.

Learning Strand-Equivariant Tokenizations of DNA with MirrorDNA

This paper introduces MirrorDNA, a DNA language model with a strand-equivariant tokenizer that improves prediction consistency across DNA strands.

Distributed Network Sensing as an Escape Strategy

The paper shows that slime mould networks can detect and escape harmful environments through reconfiguration, depending on their size and connectivity.

An expansive internal chemosensory system in the insect abdomen implicates Gustatory Receptors in diverse aspects of interoception

This study identifies an internal chemosensory system in Drosophila melanogaster's abdomen using Gustatory Receptors, revealing new roles in interoception beyond traditional feeding behaviors.

Galectin-9 drives thrombo-inflammatory circuits initiating venous thrombosis

This study identifies Galectin-9 as a driver of venous thrombo-inflammation, linking inflammation to thrombus formation through platelet activation and NETosis.

A biological light sheet links cellular voltage to mesoscopic brain dynamics

This paper introduces SPress, a method that enables high-speed, high-contrast voltage imaging of large neuronal populations in vivo with mesoscopic resolution.

MOCHI enables systematic identification of candidate independent intronic transcriptional signals from short-read RNA-seq data

MOCHI identifies candidate independent intronic transcripts from short-read RNA-seq data, revealing novel transcripts associated with cancer survival.

A single-cell transcriptomic atlas of paper wasp brains highlights Kenyon cells' role in social behavior

The paper uses single-cell transcriptomics to analyze brain cells in paper wasps, showing that Kenyon cells vary with social roles and respond to social interactions.

Can a Tiny Brain Plan? Reconstructing a Predatory Detour inthe Jumping Spider Portia labiata

This study reconstructs a wild hunt of a jumping spider, suggesting it may have planned its route to avoid detection by prey.

Highly conserved talin isoforms encode distinct mechanical responses and ligand-binding capabilities

This study examines how sequence differences between talin-1 and talin-2 affect their mechanical responses and ligand-binding capabilities, revealing distinct mechanical behaviors and new interaction sites in talin-2.