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Explore 363,000 bioRxiv and medRxiv papers across 26 biological disciplines. Save private star ratings to train your personal recommendation feed, curate reading collections, and check community reproducibility reports before building on a paper's code.
Recent preprints
Walking delays auditory processing in humans alongside a global shift in aperiodic neural activity
Xinyu Chen, Shitao Chen, Xin Zhang, Liyu Cao
bioRxiv · Nov 6, 2026 · PreprintNeuroscience
Interspecific social contacts spread gut microbiota in wild rodent communities
Aura Raulo, Eveliina Hanski, Curt Lamberth, Josh A Firth, Sarah CL Knowles
This study shows that social interactions between different rodent species can spread gut microbiota, with stronger transmission from wood mice to yellow-necked mice.
bioRxiv · Nov 6, 2026 · PreprintEcology
Elevated precontractile calcium set point is sustained by limited PMCA1 export in dystrophic muscle
Damiano Marchiafava, Kiley Hughes-Wiles, Wolfgang Stein, Xiaotian Dai, Parham Jazireian, Ashley Stanley-Copeland, Jessica Ohana, Martin F Engelke, Andrés G Vidal-Gadea
The paper shows that dystrophic muscle has an elevated precontractile calcium set point sustained by limited PMCA1 export in C. elegans and human myoblasts.
bioRxiv · Nov 6, 2026 · PreprintPathology
Development of a Pan-Proteome Multi-Epitope Vaccine Candidate Against Nipah Virus Using Reverse Vaccinology and Immunoinformatics Approaches
Rasel Khan Nishan, Md. Nahian, Bithi Akter, Tabassum Basher, Tanjum Ahmed Nodee, Irin Aminur Asha, Mostafizur Rahaman Sany, Sanjida Akter Sathy, Farzana Sharmin Shila, Mohammad Ariful Islam, Abul Kalam Azad, Md. Shariful Islam
This paper designs a multi-epitope vaccine candidate against Nipah virus using immunoinformatics and reverse vaccinology, identifying VC033_V6_BD_L03 as a lead candidate with high global and regional population coverage.
bioRxiv · Nov 6, 2026 · PreprintBioinformatics
Microscale nonrandomness revisited: An overlooked predictor of ecological change
Takeshi Miki, Kinuyo Yoneya, Ayumi Katayama, Si Ho Han, Housei Nakamura, Shungo Takeda, Hiroto Miyawaki, Tomonori Kume, Kanako Shirotsuka, Shuji Kaneko, Kensuke Seto, Silke Van den Wyngaert, Maiko Kagami
The paper introduces a framework using microscale nonrandomness to predict short-term ecological changes across diverse systems, showing improved predictive performance compared to macroscale variables.
bioRxiv · Nov 6, 2026 · PreprintEcology
Commensal Engineered Living Materials for Sustained Secretome Delivery and Wound Healing
Claire O Lois, Elizabeth A Grice, April M Kloxin, Millicent O Sullivan
This paper develops a commensal Engineered Living Material (cELM) that encapsulates bacteria to deliver a pro-healing secretome for chronic wound healing.
bioRxiv · Nov 6, 2026 · PreprintBioengineering
Disparities in avian genomic resources highlight gaps across the Global South
Vinay K. L., Chiti Arvind, Naman Goyal, Ashwin Warudkar, Sushma Reddy, V. V. Robin
The paper evaluates avian genome assemblies across geography and taxonomy, revealing underrepresentation of species in the Global South.
bioRxiv · Nov 6, 2026 · PreprintGenomics
A three-factor model can explain symmetry breaking and the n-1 rule during X-chromosome inactivation
Kaiyun Guan, Jerry M Liu, J Mauro Calabrese, Timothy C Elston
This paper introduces a three-factor mathematical model to explain symmetry breaking and the n-1 rule in X-chromosome inactivation by integrating Xist, an X-linked activator, and SPEN.
bioRxiv · Nov 6, 2026 · PreprintSystems Biology
Do divergent mitochondrial backgrounds alter the fate of nuclear alleles during hybridization and admixture?
Leah J Darwin, Rebecca Z Bachtel, Faye A Lemieux, Yevgeniy Raynes, David M Rand
The paper tests if mitochondrial backgrounds influence nuclear allele fate during hybridization, finding no evidence of such effects despite expected incompatibilities.
bioRxiv · Nov 6, 2026 · PreprintEvolutionary Biology
Developmental interactions between oscillatory and spontaneous neural activity support improvements in inhibitory control from adolescence into adulthood
Abigail M Beatty, Shane D McKeon, Daniel J Petrie, Finnegan J Calabro, Ashley C Parr, William Foran, Beatriz Luna
This study examines how developmental changes in oscillatory and spontaneous neural activity support improved inhibitory control from adolescence to adulthood using EEG data.
bioRxiv · Nov 6, 2026 · PreprintNeuroscience
Individual differences reveal shared computational structure in perceptual decision-making
Jingming Xue, Samuel F. Feng, Hua-Dong Xiong, Shensheng Wang, Robert C. Wilson
The paper uses population-level individual differences to discover shared computational components in perceptual decision-making, revealing a six-dimensional structure across datasets.
bioRxiv · Nov 6, 2026 · PreprintNeuroscience
Multimodal cellular context enables molecular phenotyping from single-molecule trajectories
Taras Redchuk, Lea Rehm, Yuan Sui, Jarno Mäkelä
The paper introduces MIST, a framework that integrates single-molecule trajectory data with cellular context to improve molecular phenotyping in E. coli.
bioRxiv · Nov 6, 2026 · PreprintBioinformatics
Real-time detection of N2 and N3 sleep from scalp and intracranial EEG
Mahmoud Alipour, Wim van Drongelen, Peter Warnke, Naoum P. Issa, Joel Voss, Joshua Jacobs, Kenneth Lee, Paola Malerba, David Satzer
This paper develops a real-time sleep stage classifier for N2 and N3 sleep using scalp and intracranial EEG, showing high accuracy and informing stimulation timing.
bioRxiv · Nov 6, 2026 · PreprintNeuroscience
Beyond Terrestrial Carnivores: Olfactory Bulb Anatomy in a Semi-Aquatic Mammal
Silvia Alejandra Fraga-Abelleira, Mateo V. Torres, Rocio Canales, Sara Ruiz-Rubio, Pablo Sanchez-Quinteiro, Irene Ortiz-Leal
This study characterizes the olfactory bulb anatomy of the Asian small-clawed otter, revealing a highly developed main olfactory bulb and a small, neurochemically distinct accessory olfactory bulb.
bioRxiv · Nov 6, 2026 · PreprintNeuroscience
Hyperactivity preferentially disrupts scotopic retinal circuits in the early stages of diabetic retinopathy
sheba annie philip, Narendra Pratap Singh, Priyanka Parida, Harikrishna Kakkatt, aravind swaminathaprasath, Lijitha Krishna Padikkappurath, Sejal Kumaravel, santhosh sethuramanujam
This study identifies scotopic retinal circuit dysfunction in early diabetic retinopathy, linking hyperactivity to rod bipolar cell abnormalities and visual impairment under low-light conditions.
bioRxiv · Nov 6, 2026 · PreprintNeuroscience
Auditory Evoked Potentials Differ from Controls and Correlate with Aspects of Cognition in Kabuki Syndrome and Rubinstein-Taybi Syndrome
Allison Kalinousky, Evan Bucklin, Rowena Ng, Lauren Meier, Haila Jiddou, Philip Fanara, Joshua B Ewen, Jacqueline Harris
This study examines auditory evoked potentials in Kabuki syndrome and Rubinstein-Taybi syndrome, finding differences from controls and correlations with cognitive aspects.
bioRxiv · Nov 6, 2026 · PreprintNeuroscience
QRAFT: Scaling coalescent-based species tree inference to one million taxa
Ashrafur Rahman, Anik Saha, Md Shamsuzzoha Bayzid
QRAFT efficiently infers species trees for up to a million taxa using coalescent-based methods, outperforming existing tools in speed and memory usage.
bioRxiv · Nov 6, 2026 · PreprintBioinformatics
Neonatal NMDA receptor blockade disrupts prefrontal cortical regulation of social affective behavior: implications for schizophrenia
Reina Tachihara, Natsumi Hayashi, Carlos Gonzalez del Rosal, Tingbi Xiong, Keita Igarashi, Takaaki Ozawa, Miyo Hori, Kazuo Yamada, Michimasa Toyoshima
This study shows that neonatal NMDA receptor blockade impairs social affective behavior in rats, linked to reduced parvalbumin interneurons in the medial prefrontal cortex.
bioRxiv · Nov 6, 2026 · PreprintNeuroscience
Probing EEG Foundation Model Attention Maps for Lightweight Interpretable Emotion Recognition
Leandros N. Arvanitopoulos, Andrei Dragomir, Christos A. Fidas, Anastasios Bezerianos
This paper proposes a lightweight, interpretable method for emotion recognition using EEG foundation models by analyzing attention maps, achieving competitive performance with fewer computations.
bioRxiv · Nov 6, 2026 · PreprintNeuroscience