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The paper uses smartphone imaging and automated analysis to phenotype flowering traits in buckwheat, identifying heritable traits and genomic regions associated with flowering patterns.

The paper uses lineage tracing and single-cell RNA sequencing to show that rhabdoid tumors converge on a limited set of transcriptional states despite clonal diversity.

The paper reanalyzes RNA-seq data from breast tumor and normal tissues to identify differentially expressed genes and assess functional enrichment, finding 120 DEGs but no significant KEGG pathways after correction.

This study shows that mitochondrial proteostasis stress causes a biphasic cortisol response, with mild stress increasing and severe stress decreasing cortisol production, linking mitochondrial function to steroidogenesis in Parkinson's disease models.

The paper identifies a new Serratia taxon in mites with genomic signs of host adaptation but phylogenetically distinct from S. symbiotica.

This study identifies and characterizes three classes of small RNAs in sperm from three cnidarian species, revealing their potential role in paternal epigenetic inheritance.

The paper shows that a vision-language model better predicts food valuation than vision-only models by encoding higher-level food attributes.

This study shows that physiological caffeine doses do not impair enteric neural crest cell migration in a mouse model, suggesting caffeine is not directly responsible for Hirschsprung disease risk.

This study shows Vorinostat reduces ongoing liver fibrosis and preserves metabolic functions by altering mesenchymal cell differentiation in a human iPSC-derived model.

The paper surveys microviruses in urban freshwater environments, finding shifts in community composition from sewage to river water, with wastewater treatment plants acting as filters.

CellReg3D integrates DNA language models and 3D genome structure to model cell-type-specific gene regulation, achieving state-of-the-art performance in predicting epigenetic marks and gene expression.

The paper introduces topoiesis, a mechanism where diffusion and geometry drive collective morphogenesis and survival in Xenopus embryos under stress.

This study shows that bL9 prevents recoding events in collided ribosomes by stabilizing their interaction and reducing frameshifting and hopping.

This study identifies the bHLH121-CAT2 module as a novel regulatory pathway that maintains root tip redox homeostasis and enhances salt tolerance in Arabidopsis independently of the SOS pathway.

This paper introduces two methods, SLED and GTD, to infer modular structure in genotype-phenotype maps by combining epistasis and pleiotropy, showing they yield similar modular architectures in yeast data.

This study identifies cholinergic and adrenergic neural signals that activate human intestinal L-cells, triggering hormone secretion and calcium waves.

This study identifies genes involved in antimicrobial tolerance of Pseudomonas aeruginosa aggregates using Tn-Seq.

SPEAR predicts cellular responses to perturbations by adaptively repositioning genes in a co-expression network using spectral encoding and generative modeling.

SafeLens uses nonlinear machine learning with statistical control to detect subtle, trial-varying neural dynamics in event-locked activity, outperforming traditional methods in sensitivity and specificity.

The paper introduces C-Fetch, a framework that retrieves 3D chromatin features using reference examples, showing improved enrichment for biologically relevant contacts compared to existing methods.