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FastaGuard is a FASTA preflight QC tool that detects structural issues in assemblies and stops pipelines before expensive analysis, with high accuracy in identifying faults.

irAEGIS predicts immune-related adverse events from pre-treatment scRNA-seq data using a pathway-guided interpretable model, outperforming existing methods and identifying biologically relevant immune programs.

This study compares movement impairments in Parkinson's disease, aging, and young adults during real and pantomimed string-pulling tasks, identifying differences in speed, workspace, and hand shaping.

This study shows the Cdh23ahl allele causes early cochlear dysfunction and phenotypic variability in mice before progressive hearing loss, with altered mechanoelectrical transduction and transcriptional changes.

CNVision is a computational framework that automates the interpretation of intragenic copy number variants by standardizing input parsing, transcript mapping, and reading-frame classification.

This paper introduces a predictive map model that explains multi-scale place field activity in hippocampal neurons and validates its predictions with experimental data.

This paper develops a microbial pathway to produce anisole from glucose using engineered Pseudomonas putida, achieving 0.57 mM anisole production.

This study shows that diet-induced obesity disrupts circadian β-cell function more in male mice than females, with time-restricted feeding partially restoring these effects.

This paper introduces Embodied Dynamic Causal Modelling to estimate effective connectivity across the brain-heart axis using multimodal data from an auditory Go/No-Go task.

Ark-ADMET selects endpoint-specific molecular representations and hyperparameters for gradient-boosted ADMET models, achieving competitive performance without new architectures or shared representations.

This study examines how cigarette smoke extract and palmitic acid affect patient-derived iPSC-RPE cells, showing increased susceptibility in AMD-derived cells with altered stress responses and function.

This study investigates the role of chromosomally-encoded Hok/Sok toxin/antitoxin systems in inhibiting phage infection in E. coli, finding that Hok proteins significantly reduce infection by BASEL phages.

This study examines how genetic architecture of flowering time in Arabidopsis thaliana changes between overwintering environments and growth chambers, finding extensive gene-by-environment interaction and environment-specific genetic effects.

This study shows that proteolytic feedback regulates quorum sensing in Pseudomonas aeruginosa by controlling RhlR stability, affecting virulence and biofilm formation.

This study evaluates the effects of anorectal care products on mucosal epithelial models, finding that hyperosmolar and surfactant-containing products cause inflammation and barrier disruption, while isotonic formulations are less harmful.

This study compares the effects of organic and inorganic fertilizers on huckleberry growth and nutritional content, finding that poultry manure enhances micronutrients more than urea, which boosts yield.

This study investigates clozapine-induced neutropenia in treatment-resistant schizophrenia using single nucleus RNA sequencing to identify cell type-specific transcriptional changes and cell-cell communication patterns.

This study examines the short-term effects of SUPERB ultrasound treatment on a chicken comb model, finding reduced vascular caliber and VEGF-A expression but no consistent collagen changes.

This study uses response latencies and error rates to unexpected questions to detect deception in narratives, finding higher values in deceptive participants and demonstrating diagnostic potential with machine learning.

This study identifies KobA as a kinesin-1-binding protein that facilitates dynein-dynactin transport to microtubule plus ends in Aspergillus nidulans.