HSP90 inhibition modulates NFB signaling in airway goblet cell metaplasia
R. A. Tudas, R. M. Gannon, A. L. Thurman, M. R. Stroik, J. Zabner, A. A. Pezzulo
This study shows HSP90 inhibition blocks NFκB signaling, preventing goblet cell metaplasia in airway epithelia, suggesting it as a therapeutic target for chronic lung diseases.
bioRxiv · May 24, 2020 · PreprintCell Biology