Author

A. A. Rubio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Organism:rat· 1 Research Focus:variant calling· 1

Frequent Co-Authors

B. N. Bell· 2 shared C. C. LaBranche· 2 shared D. C. Montefiori· 2 shared M. V. Filsinger Interrante· 2 shared P. S. Kim· 2 shared C. L. Brown· 1 shared J. G. Joyce· 1 shared J. W. Shiver· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

B. N. Bell

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A derivative of the D5 monoclonal antibody that targets the gp41 N-heptad repeat of HIV-1 with broad tier-2 neutralizing activity

A. A. Rubio, M. V. Filsinger Interrante, B. N. Bell, C. L. Brown, C. C. LaBranche, D. C. Montefiori, P. S. Kim

This paper describes the engineering of a D5 monoclonal antibody variant, D5_AR, which shows enhanced neutralizing activity against tier-2 HIV-1 strains and improved potency in cells expressing FcγRI.

bioRxiv · Oct 23, 2020Immunology

The high-affinity immunoglobulin receptor FcγRI potentiates HIV-1 neutralization via antibodies against the gp41 N-heptad repeat

D. C. Montefiori, M. V. Filsinger Interrante, B. N. Bell, A. A. Rubio, J. G. Joyce, J. W. Shiver, C. C. LaBranche, P. S. Kim

This paper shows that the FcγRI receptor enhances HIV-1 neutralization by NHR-targeting antibodies, enabling neutralization of tier-2 viruses.

bioRxiv · Aug 27, 2020Immunology