Liposomal encapsulation of polysaccharides (LEPS) as an effective vaccine strategy to protect aged hosts against S. pneumoniae infection
M. Bhalla, R. Nayerhoda, E. Y. I. Tchalla, A. Abamonte, D. Park, S. R. Simmons, B. A. Pfeifer, E. N. Bou Ghanem
This study evaluates a novel LEPS vaccine platform, showing it effectively protects aged mice against pneumococcal infections, with comparable antibody responses and improved function compared to Prevnar-13.
bioRxiv · Oct 18, 2021Microbiology