Differentiating erythroblasts adapt to turbulent flow by accelerating maturation and activating cholesterol biosynthesis.
G. Iacono, A. Abay, J. S. Gallego-Murillo, F. Aglialoro, N. Yagci, K. Fu, A. F. Svendsen, M. M. von Lindern, E. van den Akker
This study shows that erythroblasts adapt to shear stress by accelerating maturation and upregulating cholesterol biosynthesis, enhancing osmotic resistance and enucleation.
bioRxiv · Dec 8, 2023 · PreprintCell Biology