Author

E. van den Akker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

J. S. Gallego-Murillo· 2 shared M. von Lindern· 2 shared A. Abeijon-Valle· 1 shared A. Mandoli· 1 shared A. Wahl· 1 shared B. Kim· 1 shared B. P. Nicolet· 1 shared E. Heideveld· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBioengineering

J. S. Gallego-Murillo

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

BioengineeringbioRxivFeb 11, 2022

Expansion and differentiation of ex vivo cultured erythroblasts in scalable stirred bioreactors

J. S. Gallego-Murillo, G. Iacono, L. A. M. van der Wielen…·S. A. Wahl

This study scales up erythroblast culture to bioreactors, identifies optimal conditions for proliferation and differentiation, and achieves transfusion-ready cRBCs.

DOI 10.1002/bit.28193

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintAug 2, 2021

Iron-loaded deferiprone can support full hemoglobinization of cultured red blood cells in the absence of transferrin

J. S. Gallego-Murillo, N. Yagcı, E. M. Pinho…·M. von Lindern

This study shows that iron-loaded deferiprone can replace holotransferrin in erythroid cultures, supporting reticulocyte differentiation and erythroblast expansion.

DOI 10.1101/2021.08.02.454758

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintApr 10, 2020

Mouse Classical and Non-Classical Monocytes Express Comparable Levels of Chemokine Receptor CX3CR1

L. Cassetta, E. Heideveld, G. Matilionyte…·J. W. Pollard

This study shows that Cx3cr1 mRNA expression differs between circulating monocytic subsets in humans but not in mice.

DOI 10.1101/2020.04.10.035550

mouseflow cytometry

𝕏 PostBluesky

Cancer BiologybioRxivOct 29, 2018

CBFβ-MYH11 interferes with megakaryocyte differentiation via modulating a gene program that includes GATA2 and KLF1

G. Yi, A. Mandoli, L. Jussen…·J. H. A. Martens

This study shows that the CBFβ-MYH11 fusion protein inhibits megakaryocyte differentiation by disrupting the GATA2 and KLF1 gene program in inv(16) AML cells.

DOI 10.1038/s41408-019-0194-8

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivApr 12, 2018

Circular RNA expression in human hematopoietic cells is widespread and cell-type specific

B. P. Nicolet, S. Engels, F. Aglialoro…·M. C. Wolkers

The paper analyzes circRNA expression in human hematopoietic cells, finding cell-type specific patterns and increased expression during maturation.

DOI 10.1093/nar/gky721

humanexperimental assay

𝕏 PostBluesky