Author

A. F. Svendsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Abay· 1 shared A. Ausema· 1 shared A. B. Kohan· 1 shared A. de Bruin· 1 shared A. G. Groenen· 1 shared A. M. La Rose· 1 shared A. Marmolejo-Garza· 1 shared A. Mura-Meszaros· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCell Biology

A. Abay

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintDec 8, 2023

Differentiating erythroblasts adapt to turbulent flow by accelerating maturation and activating cholesterol biosynthesis.

G. Iacono, A. Abay, J. S. Gallego-Murillo…·E. van den Akker

This study shows that erythroblasts adapt to shear stress by accelerating maturation and upregulating cholesterol biosynthesis, enhancing osmotic resistance and enucleation.

DOI 10.1101/2023.12.08.570773

humanbulk RNA-seq

ImmunologybioRxivApr 10, 2022

T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice

V. Bazioti, A. M. La Rose, S. Maassen…·M. Westerterp

This study shows that T-cell cholesterol efflux via ABCA1/ABCG1 suppresses apoptosis and senescence, but paradoxically reduces atherosclerosis in middle-aged mice.

DOI 10.1038/s41467-022-31135-4

mousebulk RNA-seq

Cell BiologybioRxivAug 10, 2020

A comprehensive transcriptome signature of murine hematopoietic stem cell aging

A. F. Svendsen, D. Yang, S. Lazare…·L. Bystrykh

The paper identifies a core transcriptional aging signature in murine hematopoietic stem cells, showing increased membrane-associated gene expression and age-related heterogeneity.

DOI 10.1182/blood.2020009729

mousebulk RNA-seq