Author

A. Agrotis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

R. Ketteler· 3 shared A. Black· 1 shared A. D. Dokal· 1 shared A. Gregory· 1 shared A. Papandreou· 1 shared A. Rousseau· 1 shared A. Rutman· 1 shared A.-S. Lenaerts· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersCell Biology

R. Ketteler

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Author profile →

4 papers

Recent·Most cited

Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency

A. Papandreou, N. Singh, L. Gianfrancesco, D. Budinger, K. Barwick, A. Agrotis, C. Luft, Y. Shao, A.-S. Lenaerts, A. Gregory, S. Y. Jeong, P. Hogarth, S. Hayflick, S. Barral, J. Kriston-Vizi, , R. Ketteler

This study identifies cardiac glycosides that restore autophagy and gene expression in an iPSC model of WDR45 deficiency, suggesting potential therapeutic applications for BPAN.

bioRxiv · Sep 13, 2023 · PreprintCell Biology

Actin remodelling controls proteasome homeostasis upon stress

T. D. Williams, R. Cacioppo, A. Agrotis, A. Black, H. Zhou, A. Rousseau

The paper shows that actin remodelling facilitates RPAC translation under stress, maintaining proteasome homeostasis in yeast.

bioRxiv · Feb 9, 2022Cell Biology

Proximity interactome of LC3B in normal growth conditions

M. Nollet, A. Agrotis, F. Michailidis, A. D. Dokal, V. Rajeeve, J. Burden, T. D. Nightingale, P. Cutillas, R. Ketteler, S. Kermorgant

The paper identifies 407 proteins interacting with LC3B in normal growth conditions using APEX2 proteomics, revealing novel interactors and expanding understanding of LC3B's roles beyond autophagy.

bioRxiv · Oct 8, 2021 · PreprintCell Biology

High-content screening for rare respiratory diseases: readthrough therapy in primary ciliary dyskinesia

D. D. H. Lee, D. Cardinale, E. Nigro, C. R. Butler, A. Rutman, M. R. Fassad, R. A. Hirst, D. Moulding, A. Agrotis, E. Forsythe, D. Peckham, E. Robson, C. M. Smith, S. Somavarapu, P. L. Beales, , C. O'Callaghan

The paper develops a high-content screening method using differentiated respiratory epithelium from PCD patients to evaluate readthrough therapies for rare respiratory diseases.

bioRxiv · Feb 28, 2020 · PreprintCell Biology