LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways
A. Kshirsagar, A. Gorelik, T. Olender, T. Sapir, D. Tsuboi, I. Rosenhek-Goldian, S. Malitsky, M. Itkin, A. Argoetti, Y. Mandel-Gutfreund, S. R. Cohen, J. H. Hanna, I. Ulitsky, K. Kaibuchi, O. Reiner
This study shows LIS1 regulates mESCs viability and mechanosensitive properties through RNA-binding interactions with AGO2 and other proteins.
bioRxiv · Mar 8, 2022Cell Biology