Author

A. Ast

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Biochemistry· 1

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Boeddrich· 1 shared A. Buntru· 1 shared A. S. Wagner· 1 shared A. Z. Politi· 1 shared C. Haenig· 1 shared E. E. Wanker· 1 shared E. Sanchez-Garcia· 1 shared J. M. Ramirez-Anguita· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Boeddrich

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1 paper

Recent·Most cited

Self-assembly of mutant huntingtin exon-1 fragments into large complex fibrillar structures involves nucleated branching

A. S. Wagner, A. Z. Politi, A. Ast, K. Bravo-Rodriguez, K. Baum, A. Buntru, N. U. Strempel, L. Brusendorf, C. Haenig, A. Boeddrich, S. Plassmann, K. Klockmeier, J. M. Ramirez-Anguita, E. Sanchez-Garcia, J. Wolf, E. E. Wanker

This study investigates the self-assembly of mutant huntingtin exon-1 fragments into complex fibrillar structures, identifying two nucleation mechanisms and their role in fibril formation.

bioRxiv · Mar 15, 2018Biochemistry