Zinc Alpha-2-Glycoprotein (ZAG/AZGP1) secreted by triple-negative breast cancer promotes tumor microenvironment fibrosis.
S. Verma, S. D. Giagnocavo, M. C. Curtin, M. Arumugam, S. M. Osburn-Staker, G. Wang, A. Atkinson, D. A. Nix, D. H. Lum, J. E. Cox, K. I. Hilgendorf
This study identifies ZAG/AZGP1 as a secreted factor from triple-negative breast cancer cells that promotes fibrosis in the tumor microenvironment and is linked to poor patient prognosis.
bioRxiv · Mar 4, 2024Cancer Biology