Author

A. Audhya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 2 Assay:behavioral assay· 1 Approach:biophysical modeling· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Q. Cui· 2 shared S. Paul· 2 shared A. Laffitte· 1 shared C. A. Mendina· 1 shared C. J. Ramirez-Flores· 1 shared E. Szentgyörgyi· 1 shared J. R. Alvin· 1 shared L. J. Knoll· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiophysics

Q. Cui

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Toxoplasma gondii infection accelerates the progression of hereditary spastic paraplegia

J. R. Alvin, C. J. Ramirez-Flores, C. A. Mendina, A. Audhya, L. J. Knoll, M. M. Lettman

This study investigates how chronic Toxoplasma gondii infection affects neurodegenerative disease progression in a rat model of hereditary spastic paraplegia, finding exacerbated symptoms in infected rats.

bioRxiv · May 15, 2024 · PreprintMicrobiology

Delineating the shape of COPII coated membrane bud

S. Paul, A. Audhya, Q. Cui

The paper uses simulations to show that Sec23 and Sec24 act as spacers to determine the shape of COPII-coated membrane buds by dispersing Sar1 protomers.

bioRxiv · Feb 13, 2024Biophysics

Molecular mechanism of GTP binding- anddimerization-induced enhancement ofSar1-mediated membrane remodeling

S. Paul, A. Audhya, Q. Cui

This study uses molecular dynamics simulations to show that GTP binding enhances Sar1's membrane curvature generation by enabling full insertion of its amphipathic helix, while GDP-bound Sar1 only partially inserts, and dimerization further amplifies curvature.

bioRxiv · Jul 20, 2022Biophysics

Local regulation of lipid synthesis controls ER sheet insertion into nuclear envelope holes to complete nuclear closure

L. Penfield, R. Shankar, E. Szentgyörgyi, A. Laffitte, M. Mauro, A. Audhya, T. Müller-Reicher, S. Bahmanyar

The paper shows that CNEP-1 regulates ER sheet insertion into nuclear envelope holes during meiosis, ensuring closure without ESCRT-III.

bioRxiv · Sep 4, 2019Cell Biology