NF-κB dependent expression of A20 controls IKK repression of RIPK1 dependent cell death in activated T cells
S. Layzell, A. Barbarulo, B. Seddon
This study shows that IKK signaling in T cells protects against RIPK1-dependent cell death by phosphorylating RIPK1 and inducing A20, which modulates RIPK1 function.
bioRxiv · Sep 22, 2023 · PreprintImmunology