Plasmodium falciparum protein Pfs16 is a target for transmission-blocking antimalarial drug development
S. Yahiya, C. N. Saunders, U. Straschil, O. J. Fischer, A. Rueda-Zubiaurre, S. Haase, G. Vizcay-Barrena, S. Jordan, S. Hassan, M. J. Delves, E. W. Tate, A. Barnard, M. J. Fuchter, J. Baum
This study identifies Pfs16 as the cellular target of the N-4HCS compound DDD01035881, which blocks Plasmodium male gamete formation.
bioRxiv · Jun 14, 2021Microbiology