Evolving neoantigen profiles in colorectal cancers with DNA repair defects
G. Rospo, A. Lorenzato, N. Amirouchene-Angelozzi, A. Magri, C. Cancelliere, G. Corti, C. Negrino, V. Amodio, M. Montone, A. Bartolini, L. Barault, L. Novara, C. Isella, E. Medico, A. Bertotti, , A. Bardelli
This study tracks neoantigen profiles in colorectal cancers with DNA repair defects, finding dynamic patterns linked to antigen presentation downregulation and evolvability.
bioRxiv · Jun 11, 2019Cancer Biology