Author

A. Magri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 5 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. A. McKeating· 3 shared J. M. Harris· 3 shared A. Bardelli· 1 shared A. Bartolini· 1 shared A. Bertotti· 1 shared A. E. Kliszczak· 1 shared A. Lorenzato· 1 shared A. Otega-Prieto· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersMicrobiology

J. A. McKeating

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

VDAC1 selective molecules promote patients-derived cancer organoids death through mitochondrial-dependent metabolic interference

S. Conti Nibali, S. De Siervi, A. Magri, L. Brocca, S. Mantovani, B. Oliviero, M. U. Mondelli, V. De Pinto, C. Turato, C. Arrigoni, M. Lolicato

This paper identifies VA molecules that selectively target VDAC1 in cancer cells, causing mitochondrial distress and reduced viability, with less impact on healthy cells.

bioRxiv · Dec 4, 2023 · PreprintBiophysics

CTCF regulates hepatitis B virus cccDNA chromatin topology

M. O. Dobrica, C. S. Varghese, J. M. Harris, J. Ferguson, A. Magri, R. Arnold, C. Varnai, J. L. Parish, J. A. McKeating

This study shows that CTCF regulates HBV cccDNA chromatin topology and nucleosomal positioning, affecting viral transcription.

bioRxiv · Sep 6, 2023Microbiology

Circadian regulation of human immunodeficiency virus type 1 replication

H. Borrmann, G. Ulkar, A. E. Kliszczak, D. Ismed, M. Schilling, A. Magri, J. M. Harris, P. Balfe, S. Vasudevan, P. Borrow, X. Zhuang, J. A. McKeating

This study shows HIV-1 replication is regulated by circadian rhythms through interactions between transcription factors BMAL1, REV-ERB, and ROR, with implications for HIV therapy.

bioRxiv · Nov 30, 2022 · PreprintMicrobiology

Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure

D. A. Smith, A. Magri, R. Bowden, N. Chaturvedi, J. Fellay, J. McLauchlan, G. R. Foster, W. L. Irving, STOP-HCV Consortium, P. Simmonds, V. Pedergnana, E. Barnes, M. A. Ansari

This study identifies three HCV polymorphisms in NS2 and NS3 proteins associated with sofosbuvir treatment failure using whole genome sequencing of 507 patients.

bioRxiv · May 5, 2020Microbiology

Hypoxic gene expression in chronic hepatitis B infected patients is not observed in state-of-art in vitro and mouse infection models

P. J. Liu, J. M. Harris, E. Marchi, V. D'Arienzo, T. Michler, P. A. Wing, A. Magri, A. Otega-Prieto, M. Van de Klundert, J. Wettengel, D. Durantel, M. Dorner, P. Klenerman, U. Protzer, S. Giotis, J. A. McKeating

The paper shows hypoxia gene upregulation in chronic hepatitis B patients is not observed in in vitro or mouse models, suggesting inflammatory factors may drive this effect.

bioRxiv · Mar 27, 2020Microbiology

Evolving neoantigen profiles in colorectal cancers with DNA repair defects

G. Rospo, A. Lorenzato, N. Amirouchene-Angelozzi, A. Magri, C. Cancelliere, G. Corti, C. Negrino, V. Amodio, M. Montone, A. Bartolini, L. Barault, L. Novara, C. Isella, E. Medico, A. Bertotti, , A. Bardelli

This study tracks neoantigen profiles in colorectal cancers with DNA repair defects, finding dynamic patterns linked to antigen presentation downregulation and evolvability.

bioRxiv · Jun 11, 2019Cancer Biology