Cryo-EM Structure of a Mammalian-specific Alternative Amyloid Exon
J. Garcia-Pardo, A. Bartolome-Nafria, A. Chaves-Sanjuan, M. Gil-Garcia, C. Visentin, M. Bolognesi, S. Ricagno, S. Ventura
The paper presents the cryo-EM structure of hnRNPDL-2 amyloid fibrils, showing how alternative splicing controls RNP assembly through an amyloid exon.
bioRxiv · Aug 24, 2022 · PreprintBiochemistry