A. Bennaceur-Griscelli

This study uses patient-derived iPSCs with in vitro mutagenesis to model genomic instability in CML, identifying aberrations linked to blast crisis progression.

This study shows that BCR-ABL expression in murine ESCs promotes the formation and maintenance of hematopoietic progenitors with a molecular signature similar to wild-type HSCs.

This study identifies ENOX2 as a BCR-ABL1-dependent secreted redox protein upregulated in CML, with increased expression in patient plasma and cell lines.

This study shows chronic circadian disruption in mice increases breast cancer metastasis by enhancing stemness and creating an immunosuppressive microenvironment, which can be reversed by a CXCR2 inhibitor.