BCR-ABL promotes hematopoietic stem and progenitor cell formation in embryonic stem cells
J. Artus, A. Zenych, I. Simanic, C. Desterke, D. Clay, S. Saim, Y. Ijjeh, L. E. B. de Souza, S. Coignard, A. Bennaceur-Griscelli, A. G. Turhan, A. Foudi
This study shows that BCR-ABL expression in murine ESCs promotes the formation and maintenance of hematopoietic progenitors with a molecular signature similar to wild-type HSCs.
bioRxiv · Feb 3, 2023Cancer Biology