Coordinated poleward flux of sister kinetochore fibers drives chromosome alignment
P. Risteski, D. Bozan, M. Jagric, A. Bosilj, N. Pavin, I. M. Tolic
The paper introduces a flux-driven model for chromosome alignment, showing that length-dependent kinetochore fiber flux, regulated by Kif18A, Kif4A, and NuMA, promotes proper chromosome positioning.
Cell Reports · Aug 1, 2022Peer-reviewedCell Biology