ILRUN downregulates ACE2 expression and blocks infection of human cells by SARS-CoV-2
L. Tribolet, M. Alexander, A. Brice, P. Jansen Van Vuren, C. Rootes, K. Mara, M. McDonald, K. Bruce, T. Gough, S. Shi, C. Cowled, A. Bean, C. R. Stewart
This study shows that ILRUN inhibits SARS-CoV-2 replication by downregulating ACE2 expression and blocking viral entry into human cells.
bioRxiv · Nov 13, 2020Cell Biology