Author

C. Rootes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

C. Cowled· 2 shared C. R. Stewart· 2 shared L. Tribolet· 2 shared P. Jansen Van Vuren· 2 shared A. Bean· 1 shared A. Brice· 1 shared A. G. D. Bean· 1 shared A. M. Brice· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

C. Cowled

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Ribosome-profiling reveals restricted post transcriptional ex-pression of antiviral cytokines and transcription factors during SARS-CoV-2 infection

M. R. Alexander, A. M. Brice, P. Jansen Van Vuren, C. Rootes, L. Tribolet, C. Cowled, A. G. D. Bean, C. R. Stewart

This study uses ribosome profiling to show that SARS-CoV-2 restricts post-transcriptional expression of antiviral cytokines and transcription factors in human lung cells.

bioRxiv · Mar 3, 2021Microbiology

ILRUN downregulates ACE2 expression and blocks infection of human cells by SARS-CoV-2

L. Tribolet, M. Alexander, A. Brice, P. Jansen Van Vuren, C. Rootes, K. Mara, M. McDonald, K. Bruce, T. Gough, S. Shi, C. Cowled, A. Bean, C. R. Stewart

This study shows that ILRUN inhibits SARS-CoV-2 replication by downregulating ACE2 expression and blocking viral entry into human cells.

bioRxiv · Nov 13, 2020Cell Biology