Nrf2 regulates the activation-driven expansion of CD4+ T-cells by differentially modulating glucose and glutamine metabolism
A. Tripathi, D. Dasgupta, A. Pant, A. Bugbee, N. K. Yellapu, B. H. Y. Choi, s. Giri, K. Pyaram
This study shows Nrf2 modulates CD4+ T-cell activation and expansion by altering glucose and glutamine metabolism, offering insights for improving immunotherapies.
bioRxiv · Apr 18, 2024 · PreprintImmunology