S. Giri

The effects of Paternal Radiofrequency Radiation Exposure on Sperm and Testicular Integrity in F1-Male Swiss Albino Mice

This study investigates the effects of paternal radiofrequency radiation exposure on sperm and testicular integrity in F1 male mice, finding reduced sperm count and germinal epithelium depletion in offspring.

Blood-based targeted metabolipidomics reveals altered omega fatty acid-derived lipid mediators in relapsing-remitting multiple sclerosis patients

The paper identifies altered omega fatty acid-derived lipid mediators in RRMS patients using metabolipidomics, suggesting their potential as biomarkers for diagnosis and prognosis.

Profiling blood-based neural biomarkers and cytokines in experimental autoimmune encephalomyelitis model of multiple sclerosis using single molecule array technology

This study uses SIMOA to profile blood-based neural biomarkers and cytokines in EAE models, identifying NFL, GFAP, and IL-10 as potential predictors of disease activity.

Immuno-Responsive Gene-1: The Mitochondrial Key to Th17 Cell Pathogenicity in CNS Autoimmunity

This study identifies Irg1 as a protective gene that negatively regulates pathogenic Th17 cells in CNS autoimmunity using knockout mice and single-cell RNA sequencing.

Parasite-Induced IFN-g Regulates Host Defense via CD115 and mTOR-Dependent Mechanism of Tissue-Resident Macrophage Death

This study shows that IFN-gamma induces CD115 and mTOR-dependent death of tissue-resident macrophages, enhancing host resistance to Toxoplasma gondii.

COP9 Signalosome Promotes Neointimal Hyperplasia via Deneddylation and CSN5-Mediated Nuclear Export

This study shows that the COP9 signalosome promotes neointimal hyperplasia via deneddylation and CSN5-mediated nuclear export of p27 in vascular smooth muscle cells.

Intermittent Fasting induced ketogenesis inhibits mouse epithelial ovarian tumors by promoting anti-tumor T cell response.

This study shows that intermittent fasting inhibits mouse epithelial ovarian tumors by enhancing anti-tumor T cell responses through metabolic changes and immune modulation.

Unraveling the Potential Role of Tecomella undulata in Experimental NASH

This study investigates the effects of Tecomella undulata on NASH in mice, finding it reduces weight, insulin resistance, liver enzymes, and inflammation, comparable to Saroglitazar.

ZRC3308 monoclonal antibody cocktail shows protective efficacy in Syrian hamsters against SARS-CoV-2 infection

The paper develops a monoclonal antibody cocktail (ZRC-3308) effective against multiple SARS-CoV-2 variants in Syrian hamsters.

Assessment of immunogenicity and protective efficacy of ZyCoV-D DNA vaccine candidates in Rhesus macaques against SARS-CoV-2 infection

This study evaluates two doses of ZyCoV-D DNA vaccine in rhesus macaques, finding that the 2mg dose via Needle Free Injection System provides better immune response and protection against SARS-CoV-2.

Estimation of the Acetylcholinesterase activity of honey bees in Nepal

This study measures Acetylcholinesterase activity in honey bees from Nepal, finding increased AChE and protein levels in winter samples and species-specific differences.

Obligate cross-feeding expands the metabolic niche of bacteria

This study shows that obligate cross-feeding between bacterial species expands their collective metabolic niche space more than it contracts it, especially between distantly related specialists.

Metabolic dissimilarity determines the establishment of cross-feeding interactions in bacteria

The study shows that metabolic dissimilarity between bacterial strains promotes cross-feeding interactions, as demonstrated through cocultivation experiments and in-silico analysis of gut microbiota.