Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infections.
J. Osowicki, H. R. Frost, K. I. Azzopardi, A. L. Whitcombe, R. McGregor, L. H. Carlton, C. Baker, L. Fabri, M. Pandey, M. F. Good, J. R. Carapetis, M. J. Walker, P. R. Smeesters, P. V. Licciardi, N. J. Moreland, , A. C. Steer
The paper examines antibody responses to S. pyogenes antigens in individuals with and without pharyngitis, finding differences in IgG and IgA levels and correlations with prior immunity.
bioRxiv · Apr 20, 2024 · PreprintImmunology