Biomechanics and Myofibrillar Alignment Enhance Contractile Development and Reproducibility in Stem Cell Derived Cardiac Muscle
Y.-C. Tsan, Y.-T. Zhao, S. J. DePalma, A. Capilnasiu, Y.-W. Wu, B. Elder, I. Panse, S. Friedline, T. S. O'Leary, N. Wubshet, K. K. Y. Ho, M. J. Previs, D. Nordsletten, B. M. Baker, L. L. Isom, , A. S. Helms
This study develops a 2D platform to enhance contractile development and reproducibility in stem cell-derived cardiac muscle by controlling biomechanics and myofibrillar alignment.
bioRxiv · May 23, 2021 · PreprintCell Biology