Tumoroscope: a probabilistic model for mapping cancer clones in tumor tissues
S. Darvish Shafighi, A. Geras, B. Jurzysta, A. Sahaf Naeini, I. Filipiuk, L. Raczkowski, H. Toosi, L. Koperski, K. Thrane, C. Engblom, J. Mold, X. Chen, J. Hartman, D. Nowis, A. Carbone, , E. Szczurek
Tumoroscope maps cancer clones in tumor tissues by integrating spatial transcriptomics, whole exome sequencing, and pathological images to reveal spatial patterns and clone-specific gene expression.
bioRxiv · Sep 22, 2022 · PreprintCancer Biology