Author

K. Thrane

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Approach:deep learning· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

C. Engblom· 2 shared H. Toosi· 2 shared J. Hartman· 2 shared J. Lagergren· 2 shared X. Chen· 2 shared A. Andersson· 1 shared A. Carbone· 1 shared A. Geras· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

C. Engblom

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2 papers

Recent·Most cited

Spatial transcriptomics of T and B cell receptors uncovers lymphocyte clonal dynamics in human tissue.

C. Engblom, K. Thrane, Q. Lin, A. Andersson, H. Toosi, X. Chen, E. Steiner, G. Mantovani, M. Hagemann-Jensen, S. Saarenpaa, M. Jangard, J. Michaelsson, J. Hartman, J. Lagergren, J. E. Mold, , J. Frisen

This paper introduces Spatial VDJ, a spatial transcriptomics method that maps T and B cell receptors in human tissue, revealing clonal dynamics and spatial organization of lymphocytes.

bioRxiv · Nov 22, 2022 · PreprintImmunology

Tumoroscope: a probabilistic model for mapping cancer clones in tumor tissues

S. Darvish Shafighi, A. Geras, B. Jurzysta, A. Sahaf Naeini, I. Filipiuk, L. Raczkowski, H. Toosi, L. Koperski, K. Thrane, C. Engblom, J. Mold, X. Chen, J. Hartman, D. Nowis, A. Carbone, , E. Szczurek

Tumoroscope maps cancer clones in tumor tissues by integrating spatial transcriptomics, whole exome sequencing, and pathological images to reveal spatial patterns and clone-specific gene expression.

bioRxiv · Sep 22, 2022 · PreprintCancer Biology