The pathognomonic FOXL2 C134W mutation alters DNA binding specificity
A. Carles, G. Trigo-Gonzalez, R. Cao, S.- W. G. Cheng, M. Moksa, M. Bilenky, G. B. Morin, D. G. Huntsman, M. Hirst
This study investigates the molecular effects of the FOXL2 C134W mutation in AGCT by analyzing DNA binding and transcriptome changes in engineered cell lines.
bioRxiv · Mar 20, 2020Cancer Biology