DNA damage independent inhibition of NF-κB transcription by anthracyclines
A. Chora, D. Pedroso, N. Pejanovic, E. Kyriakou, H. Colaco, R. Gozzelino, A. Barros, K. Willmann, T. Velho, C. Moita, I. Santos, S. Carvalho, F. Martins, J. Ferreira, S. Almeida, , L. F. Moita
This study shows anthracyclines inhibit NF-κB transcription without DNA damage, affecting inflammation independently of their DNA-damaging effects.
bioRxiv · Apr 27, 2020Immunology