I. Santos

Combined Dendritic Cell And Anti-TIGIT Immunotherapy Potentiate Trail+ Memory NK Cells Against HIV-1 Infected Cells

Combining dendritic cell stimulation with anti-TIGIT antibodies enhances memory NK cell cytotoxicity against HIV-1 infected CD4+ T cells in vitro and in vivo.

Sst+ GPi output neurons provide direct feedback to key nodes of the basal ganglia and drive behavioral flexibility.

This study identifies Sst+ GPi neurons that provide feedback to basal ganglia nodes and influence behavioral flexibility during learning.

ART duration and immunometabolic state determine efficacy of DC-based treatment restoring functional HIV- specific CD8+ T cells in PLWH.

This study shows that ART duration affects CD8+ T cell function in HIV-1 patients, with longer ART improving DC-based immunotherapy outcomes through specific immunometabolic changes.

TAILORED DC INDUCE PROTECTIVE HIV-1 SPECIFIC POLYFUNCTIONAL CD8+ T CELLS IN THE LYMPHOID TISSUE FROM HUMANIZED BLT MICE

This study shows that TBK1-primed dendritic cells reduce HIV-1 disease progression in humanized mice by enhancing CD8+ T cell responses.

DNA damage independent inhibition of NF-κB transcription by anthracyclines

This study shows anthracyclines inhibit NF-κB transcription without DNA damage, affecting inflammation independently of their DNA-damaging effects.

CXCL5-mediated recruitment of neutrophils into the peritoneal cavity of Gdf15-deficient mice protects against abdominal sepsis

This study shows that GDF15 deficiency in mice protects against abdominal sepsis by enhancing CXCL5-mediated neutrophil recruitment to the peritoneum, improving bacterial control.

Drug related and psychopathological symptoms in HIV-positive men who have sex with men who inject drugs during sex (Slamsex): Data from the U-SEX GESIDA 9416 Study.

This study examines HIV-positive men who have sex with men who inject drugs during sex (slamsex) and finds higher rates of psychopathology, drug-related symptoms, and STIs compared to those who engage in chemsex without injection.

Environments with a high probability of incompatible crosses do not select for mate avoidance in spider mites

The paper investigates whether Wolbachia-induced cytoplasmic incompatibility selects for mate avoidance in spider mites, finding no evolution of mate choice despite genetic variation in mating duration.

Despite reproductive interference, the net outcome of reproductive interactions among spider mite species is not necessarily costly

The study examines reproductive interactions among spider mite species, finding that while mating with heterospecifics can have negative or positive effects on fecundity and sex ratio, the overall net effect is weak.