Author

A. Crabbe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

T. Coenye· 3 shared A. A. Dandekar· 1 shared A. Sass· 1 shared E. Abatih· 1 shared F. Van Nieuwerburgh· 1 shared H. Van Acker· 1 shared I. Vandenbussche· 1 shared K. L. Asfahl· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMicrobiology

T. Coenye

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identification of echinacoside as a tobramycin potentiator against Pseudomonas aeruginosa aggregates

Y.-M. Cai, A. Crabbe, T. Coenye

The paper identifies echinacoside as a tobramycin potentiator that reduces c-di-GMP levels and aggregate size in Pseudomonas aeruginosa, enhancing antibiotic efficacy against biofilms.

bioRxiv · Feb 9, 2024 · PreprintMicrobiology

Non-hierarchical, RhlR-regulated acyl-homoserine lactone quorum sensing in a cystic fibrosis isolate of Pseudomonas aeruginosa

R. L. Cruz, K. L. Asfahl, S. Van den Bossche, T. Coenye, A. Crabbe, A. A. Dandekar

The paper shows that a LasR-null Pseudomonas aeruginosa isolate uses RhlR for quorum sensing and virulence, suggesting RhlR as a therapeutic target in chronic infections.

bioRxiv · Sep 2, 2019Microbiology

Various evolutionary trajectories lead to loss of the tobramycin-potentiating activity of the quorum sensing inhibitor baicalin hydrate in Burkholderia cenocepacia biofilms

A. Sass, L. Slachmuylders, H. Van Acker, I. Vandenbussche, L. Ostyn, A. Crabbe, L. Chiarelli, S. Buroni, F. Van Nieuwerburgh, E. Abatih, T. Coenye

This study shows that biofilms of Burkholderia cenocepacia develop resistance to the antibiotic-potentiating activity of baicalin hydrate through various genetic changes.

bioRxiv · Sep 6, 2018Microbiology