Author
A. A. Dandekar
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 14 mutual co-author links7 papers
Recent·Most cited
- MicrobiologybioRxiv
Tripartite interactions between filamentous Pf4 bacteriophage, Pseudomonas aeruginosa, and bacterivorous nematodes
C. M. Schwartzkopf, A. J. Robinson, M. Ellenbecker…·P. R. Secor
This study shows that curing Pseudomonas aeruginosa of Pf4 phage infection increases virulence in C. elegans by enhancing PQS quorum sensing and pyocyanin production, but nematodes unable to detect bacterial pigments are more susceptible to the Pf4-cured strain.
DOI 10.1371/journal.ppat.1010925 - MicrobiologybioRxiv
Genetic and transcriptomic characteristics of RhlR-dependent quorum sensing in cystic fibrosis isolates of Pseudomonas aeruginosa
K. L. Asfahl, N. E. Smalley, A. P. Chang, A. A. Dandekar
The paper examines genetic and transcriptomic features of RhlR-dependent quorum sensing in Pseudomonas aeruginosa isolates from cystic fibrosis patients, identifying a core regulon and highlighting the importance of RhlR in chronic infections.
DOI 10.1128/msystems.00113-22 - MicrobiologybioRxiv
Evolution of the quorum sensing regulon in cooperating populations of Pseudomonas aeruginosa
N. E. Smalley, A. L. Schaefer, K. L. Asfahl…·A. A. Dandekar
The paper shows that long-term growth of Pseudomonas aeruginosa under limited QS conditions reduces the number of QS-activated genes by 45-70%.
DOI 10.1128/mbio.00161-22 - MicrobiologybioRxiv
Tobramycin adaptation enhances policing of social cheaters in Pseudomonas aeruginosa
R. Abisado, J. H. Kimbrough, B. M. McKee…·J. R. Chandler
This study shows tobramycin suppresses lasR mutants in Pseudomonas aeruginosa by directly targeting cheaters and selecting for mutations that enhance pyocyanin-mediated policing.
DOI 10.1128/aem.00029-21 - MicrobiologybioRxiv
Burkholderia thailandensis methylated hydroxy-alkylquinolines: biosynthesis and antimicrobial activity in co-culture experiments
J. R. Klaus, C. Majerczyk, S. Moon…·J. R. Chandler
This study identifies N-oxidated methyl-alkenylquinolines (HMAQ-NOs) as antimicrobial compounds produced by Burkholderia thailandensis, showing they are 50-fold more active than their non-oxidized counterparts against Bacillus subtilis.
DOI 10.1128/aem.01452-20 - MicrobiologybioRxiv
Non-hierarchical, RhlR-regulated acyl-homoserine lactone quorum sensing in a cystic fibrosis isolate of Pseudomonas aeruginosa
R. L. Cruz, K. L. Asfahl, S. Van den Bossche…·A. A. Dandekar
The paper shows that a LasR-null Pseudomonas aeruginosa isolate uses RhlR for quorum sensing and virulence, suggesting RhlR as a therapeutic target in chronic infections.
DOI 10.1128/mbio.00532-20