Genetic differences in the aryl hydrocarbon receptor and CYP1A2 affect susceptibility to developmental polychlorinated biphenyl exposure in mice: Relevance to studies of human neurological disorders
K. Klinefelter, M. K. Hooven, C. Bates, B. T. Colter, A. Dailey, S. K. Infante, I. Kania-Korwel, H.-J. Lehmler, A. Lopez-Juarez, C. P. Ludwig, C. P. Curran
This study shows genetic differences in Ahr and Cyp1a2 genes affect susceptibility to developmental PCB exposure in mice, with no strong link to Parkinson's disease risk.
bioRxiv · Sep 27, 2017Pharmacology & Toxicology