Niclosamide loaded Eudragit EPO nanoparticles show enhanced Candida biofilm penetration, trigger biofilm detachment and protect from mucosal candidiasis
Y. Sutar, S. Nabeela, S. Singh, A. Alqarihi, N. V. Solis, T. Gebremariam, S. Filler, A. Ibrahim, A. Date, P. Uppuluri
This study identifies Niclosamide as a drug that disrupts Candida biofilms and develops nanoparticles to enhance its efficacy against drug-resistant strains.
bioRxiv · Jun 2, 2022 · PreprintMicrobiology