The evolutionary history of 2,658 cancers
M. Gerstung, C. Jolly, I. Leshchiner, S. C. Dentro, S. Gonzalez Rosado, D. Rosebrock, T. J. Mitchell, Y. Rubanova, P. Anur, K. Yu, M. Tarabichi, A. Deshwar, J. Wintersinger, K. Kleinheinz, I. Vazquez-Garcia, , Spellman
This study uses whole-genome sequencing of cancer samples to reconstruct the evolutionary history of 39 cancer types, identifying early and late-stage mutational patterns and driver genes.
bioRxiv · Sep 12, 2018Cancer Biology