Author

A. Distefano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

G. Li Volti· 5 shared M. Caruso· 5 shared R. Emma· 5 shared R. Polosa· 5 shared S. Rust· 5 shared A. Arsenijevic· 3 shared A. Giordano· 3 shared R. Pulvirenti· 3 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersPharmacology & Toxicology

G. Li Volti

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Toxicological evaluation of Vanillin Flavor in E-Liquid Aerosols on Endothelial Cell Function: Findings from the Replica Project

R. Emma, A. Sun, K. Partsinevelos, S. Rust, V. Volarevic, R. Lesmana, A. Giordano, H. Goenawan, M. I. Barliana, A. Arsenijevic, N. Kastratovic, V. Markovic, B. Spasic, A. Distefano, L. Orlando, , G. Li Volti

This study replicates and clarifies findings from a previous study on vanillin's effects in e-cigarette aerosols, showing ethanol, not vanillin, causes endothelial dysfunction.

bioRxiv · Jan 20, 2024Pharmacology & Toxicology

Cytotoxicity, Mutagenicity and Genotoxicity of Electronic Cigarettes Emission Aerosols Compared to Cigarette Smoke: the REPLICA project

R. Emma, V. Fuochi, A. Distefano, S. Rust, F. Zadjali, M. A. Tobi, R. Zadjali, Z. Alharthi, R. Pulvirenti, P. M. Furneri, R. Polosa, M. Caruso, G. Li Volti

The REPLICA project replicates in vitro studies on e-cigarette and cigarette smoke, finding e-cigarette aerosol is less cytotoxic, mutagenic, and genotoxic than cigarette smoke.

bioRxiv · Oct 28, 2022Biochemistry

Comparative assessment of electronic nicotine delivery systems aerosol and cigarette smoke on endothelial cell migration: the Replica Project

M. Caruso, R. Emma, A. Distefano, S. Rust, K. Poulas, A. Giordano, V. Volarevic, K. Mesiakaris, S. Boffo, A. Arsenijevic, G. Karanasios, R. Pulvirenti, A. Ilic, A. Canciello, P. Zuccarello, , G. Li Volti

The study replicates previous findings showing that e-cig and heated tobacco product aerosols have reduced effects on endothelial cell migration compared to cigarette smoke.

bioRxiv · Dec 23, 2021Pharmacology & Toxicology

Electronic nicotine delivery systems exhibit reduced bronchial epithelial cells toxicity compared to cigarette: The Replica Project

M. Caruso, R. Emma, A. Distefano, S. Rust, K. Poulas, F. Zadjali, S. Boffo, V. Volarevic, K. Mesiakaris, M. A. Tobi, A. Giordano, A. Arsenijevic, P. Zuccarello, M. Ferrante, R. Polosa, , Replica Project Group

This study replicates and validates previous research on the cytotoxicity of cigarette smoke and ENDS aerosol, finding reduced toxicity of ENDS products.

bioRxiv · May 5, 2021Pharmacology & Toxicology

Screening of different cytotoxicity methods for the assessment of ENDS toxicity relative tobacco cigarettes

M. Caruso, R. Emma, S. Rust, A. Distefano, G. Carota, R. Pulvirenti, R. Polosa, G. Li Volti

The paper compares cytotoxicity assays to evaluate the toxicity of ENDS products relative to tobacco cigarettes.

bioRxiv · Feb 25, 2021Pharmacology & Toxicology