S. Rust

Visualization of Type IV-A1 CRISPR-mediated repression of gene expression and plasmid replication

This study examines the CRISPRi effects of the Type IV-A1 CRISPR-Cas system in Pseudomonas oleovorans and Escherichia coli using synthetic crRNAs, revealing long-range gene repression and plasmid targeting.

Toxicological evaluation of Vanillin Flavor in E-Liquid Aerosols on Endothelial Cell Function: Findings from the Replica Project

This study replicates and clarifies findings from a previous study on vanillin's effects in e-cigarette aerosols, showing ethanol, not vanillin, causes endothelial dysfunction.

Cytotoxicity, Mutagenicity and Genotoxicity of Electronic Cigarettes Emission Aerosols Compared to Cigarette Smoke: the REPLICA project

The REPLICA project replicates in vitro studies on e-cigarette and cigarette smoke, finding e-cigarette aerosol is less cytotoxic, mutagenic, and genotoxic than cigarette smoke.

Nicotine measurement on Cambridge Filter PADs: an interlaboratory comparison to evaluate exposure by different electronic devices and traditional cigarette

This study evaluates interlaboratory consistency in nicotine measurement using Cambridge Filter PADs across different electronic devices and traditional cigarettes.

Comparative assessment of electronic nicotine delivery systems aerosol and cigarette smoke on endothelial cell migration: the Replica Project

The study replicates previous findings showing that e-cig and heated tobacco product aerosols have reduced effects on endothelial cell migration compared to cigarette smoke.

Electronic nicotine delivery systems exhibit reduced bronchial epithelial cells toxicity compared to cigarette: The Replica Project

This study replicates and validates previous research on the cytotoxicity of cigarette smoke and ENDS aerosol, finding reduced toxicity of ENDS products.

Screening of different cytotoxicity methods for the assessment of ENDS toxicity relative tobacco cigarettes

The paper compares cytotoxicity assays to evaluate the toxicity of ENDS products relative to tobacco cigarettes.

Nicotine dosimetry and stability in Cambridge Filter PADs (CFPs) following different smoking regimen protocols and condition storage

This study evaluates nicotine dosimetry and stability in Cambridge Filter PADs under different smoking protocols and storage conditions, finding that -80°C storage preserves nicotine content.

A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.

This paper demonstrates that a single dose of an antibody-drug conjugate targeting the trypanosome receptor HpHbR completely cures a stage 1 mouse model of African trypanosomiasis.