Author

A. Sun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cancer Biology· 2 Biophysics· 1 Cell Biology· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

Y. Chen· 2 shared Z. Chen· 2 shared A. A. Amir· 1 shared A. Arsenijevic· 1 shared A. B. Truong· 1 shared A. Biswas· 1 shared A. Distefano· 1 shared A. Duensing· 1 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersBioengineering

Y. Chen

Mutual co-authors in cluster

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9 papers

Recent·Most cited

Multi-parametric thrombus profiling microfluidics detects intensified biomechanical thrombogenesis associated with hypertension and aging

M. Din, S. Paul, S. Ullah, H. Yang, R.-G. Xu, N. A. Z. Abidin, A. Sun, Y. C. Chen, R. Gao, B. Chowdhury, F. Zhou, S. Rogers, M. Miller, A. Biswas, L. Hu, , Y. Chen

This paper introduces a microfluidics-based thrombus profiling assay that detects intensified biomechanical thrombogenesis in hypertension and aging, revealing a GPIb-integrin mechanosensing axis hyperactivity mechanism.

bioRxiv · Jun 11, 2024Bioengineering

Toxicological evaluation of Vanillin Flavor in E-Liquid Aerosols on Endothelial Cell Function: Findings from the Replica Project

R. Emma, A. Sun, K. Partsinevelos, S. Rust, V. Volarevic, R. Lesmana, A. Giordano, H. Goenawan, M. I. Barliana, A. Arsenijevic, N. Kastratovic, V. Markovic, B. Spasic, A. Distefano, L. Orlando, , G. Li Volti

This study replicates and clarifies findings from a previous study on vanillin's effects in e-cigarette aerosols, showing ethanol, not vanillin, causes endothelial dysfunction.

bioRxiv · Jan 20, 2024Pharmacology & Toxicology

Three-dimensional imaging and quantification of mouse ovarian follicles via optical coherence tomography

M. M. Amaral, A. Sun, Y. Li, C. Ren, A. B. Truong, S. Nigam, Z. Jiao, P. Wang, C. Zhou

This study uses SD-OCT to identify and quantify ovarian follicles in mice, showing agreement with histology and improved image contrast for follicle analysis.

bioRxiv · Jan 23, 2023Bioengineering

The compact CasPi (Cas12l) bracelet "provides" a unique structural platform for DNA manipulation

A. Sun, C. Li, Z. Chen, S. Zhang, D. Li, Y. Yang, L.-Q. Li, Y. Zhao, K. Wang, Z. Li, J. Liu, S. Liu, J. Wang, J.-J. G. Liu

The paper identifies a new CRISPR-Cas12l system from metagenomes, showing it cleaves DNA with a unique PAM and forms a bracelet structure for gene editing.

bioRxiv · Dec 16, 2022Biophysics

Targeting the translational machinery in gastrointestinal stromal tumors (GIST) - a new therapeutic vulnerability

D. M. Lee, A. Sun, S. S. Patil, L. Liu, A. V. Rao, P. T. Trent, A. A. Amir, C. Liu, J. L. Rausch, L. D. Presutti, A. Kaczorowski, F. Schneider, N. Amankulor, M. Shuda, A. Duensing

This study shows that homoharringtonine (HHT) effectively inhibits KIT-dependent GIST growth by reducing protein synthesis, even in imatinib-resistant models.

bioRxiv · Sep 1, 2021Cancer Biology

Oxidized LDL but not angiotensin II induces the interaction between LOX-1 and AT1 receptors

L. Lin, N. Zhou, L. Kang, Q. Wang, J. Wu, X. Wang, C. Yang, G. Zhang, Y. Chen, H. Jiang, R. Chen, X. Yang, A. Sun, H. Gong, J. Ren, , Y. Zou

This study shows Ox-LDL, not AngII, induces LOX-1 and AT1-R interaction, leading to cardiomyocyte hypertrophy via Gq protein activation.

bioRxiv · Dec 14, 2020 · PreprintCell Biology

Preliminary Minimum Reporting Requirements for Reporting In-Vivo Neural Interface Research: I. Implantable Neural Interfaces

C. D. Eiber, J. Delbeke, J. Cardoso, M. de Neeling, S. John, C. W. Lee, J. Skefos, A. Sun, D. Prodanov, Z. McKinney

This paper outlines preliminary reporting guidelines for implantable neural interface research developed by IEEE WG P2794 to improve transparency, reproducibility, and integration of neurotechnologies.

bioRxiv · Nov 18, 2020Bioengineering

Microbiota Accelerates Age-Related CpG island Methylation in Colonic Mucosa

A. Sun, L. Cole, S. Maegawa, P. H. Park, K. Keith, J. Madzo, J. Jelinek, C. Jobin, J.-P. J. Issa

The paper shows microbiota accelerates age-related CpG island methylation in colonic mucosa, similar to cancer, and interacts with inflammation to enhance methylation changes.

bioRxiv · Aug 28, 2020 · PreprintMicrobiology

Contextual Tumor Suppressor Function Of T Cell Death-Associated Gene 8 (TDAG8) In Hematological Malignancies

C. R. Justus, E. J. Sanderlin, L. Dong, A. Sun, J.-T. Chi, K. Lertpiriyapong, L. V. Yang

This study shows TDAG8 gene expression is reduced in blood cancers and its restoration suppresses tumor growth and metastasis under acidotic conditions.

bioRxiv · Jun 1, 2017Cancer Biology