Overexpression of AMPKγ2 increases AMPK signaling to augment human T cell metabolism and function
E. Braverman, M. McQuaid, D. Monlish, A. Dobbs, M. Ramsey, A. Ramgopal, H. Brown, C. Byersdorfer
This study shows that overexpressing AMPKγ2 in human T cells enhances oxidative metabolism, improves expansion, and boosts function under low glucose conditions.
bioRxiv · Oct 1, 2022Immunology